Transjugular Liver Biopsy (TJLB) in India

Transjugular Liver Biopsy (TJLB) is a minimally invasive procedure used to obtain liver tissue for diagnosis when conventional percutaneous biopsy is risky, such as in patients with bleeding disorders, ascites, or high-risk liver disease. The procedure is performed via the jugular vein, avoiding direct puncture of the liver through the abdominal wall.

India provides advanced interventional radiology services, experienced hepatologists, and comprehensive post-procedure care.

Indications for Transjugular Liver Biopsy

  • Coagulopathy or bleeding disorders where percutaneous biopsy is risky

  • Ascites or fluid accumulation around the liver

  • Evaluation of chronic liver disease, hepatitis, or cirrhosis

  • Assessment of liver transplant rejection or graft function

  • Diagnosis of liver tumors when standard biopsy is contraindicated

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Symptoms or Conditions Addressed

  • Unexplained liver enzyme abnormalities

  • Chronic jaundice or liver dysfunction

  • Ascites or fluid retention

  • Suspected liver fibrosis or cirrhosis

  • Monitoring after liver transplantation


Procedure Overview

  1. Pre-procedure Assessment

    • Blood tests (including coagulation profile), liver function tests

    • Imaging (Ultrasound, CT) to plan the procedure

    • Assessment for sedation and patient fitness

  2. TJLB Procedure

    • Performed under local anesthesia with sedation

    • A catheter is inserted through the jugular vein in the neck

    • Guided into the hepatic vein and a small tissue sample is obtained

    • Imaging ensures safe access and prevents complications

  3. Post-procedure Care

    • Short hospital stay: usually 1 day

    • Monitoring for bleeding or neck/abdominal discomfort

    • Rest and avoidance of strenuous activity for 24–48 hours

    • Follow-up to review biopsy results


Benefits of Transjugular Liver Biopsy

  • Minimally invasive with low risk of bleeding

  • Safe for patients with ascites or coagulation disorders

  • Can be performed even in critically ill patients

  • Provides adequate liver tissue for diagnosis and staging

  • Short hospital stay and faster recovery


Transjugular Liver Biopsy Cost in India

Table 1: Average Transjugular Liver Biopsy Cost in India

Procedure TypeMinimum Cost (INR)Maximum Cost (INR)Approx. USD Range
TJLB Procedure₹1,00,000₹2,50,000$1,200 – $3,010
Pre-procedure Imaging & Tests₹20,000₹50,000$240 – $600
Post-procedure Care & Medications₹15,000₹50,000$180 – $600

Factors Affecting Cost

  1. Hospital facilities – Advanced interventional radiology centers may charge more

  2. Patient condition – Critical illness or co-morbidities may require extra monitoring

  3. Imaging and lab tests – Pre- and post-procedure evaluations

  4. Complexity of biopsy – Single vs multiple tissue samples

  5. Follow-up care – Consultation and review of biopsy results


Who Should Consider Transjugular Liver Biopsy?

  • Patients with bleeding disorders or coagulation issues

  • Individuals with ascites or difficult liver access

  • Patients needing diagnostic liver tissue safely

  • Candidates referred by hepatologists, gastroenterologists, or transplant teams

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