Pituitary Tumor Treatment in India

Pituitary tumors are abnormal growths in the pituitary gland, a small gland at the base of the brain that regulates hormones controlling growth, metabolism, and reproduction. Most pituitary tumors are benign (adenomas), but their effect on hormone production and nearby structures can cause significant health issues.

Treatment in India combines surgery, medical therapy, and radiation, depending on the size, type, and impact of the tumor.

Symptoms of Pituitary Tumors

Symptoms depend on whether the tumor is functioning (hormone-secreting) or non-functioning:

  • Hormonal symptoms

    • Overproduction: Cushing’s disease (excess cortisol), Acromegaly (excess growth hormone), Hyperprolactinemia (excess prolactin).

    • Underproduction: Fatigue, infertility, hypothyroidism.

  • Pressure symptoms

    • Headaches

    • Vision problems (loss of peripheral vision, double vision)

    • Nausea and vomiting

    • Facial pain or numbness (rare in larger tumors)

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Types of Pituitary Tumors

  1. Functioning Tumors – Secrete excess hormones (e.g., prolactinomas, GH-secreting tumors).

  2. Non-Functioning Tumors – Do not produce hormones but can press on nearby structures.

  3. Pituitary Carcinomas – Very rare malignant tumors.


Diagnosis of Pituitary Tumors

  • MRI/CT Scan of the Brain: Detects tumor size and location.

  • Hormone Blood Tests: Prolactin, cortisol, growth hormone, thyroid and sex hormones.

  • Visual Field Testing: To check optic nerve involvement.

  • Stimulation/Suppression Tests: Confirm abnormal hormone secretion.


Treatment Options for Pituitary Tumors in India

1. Surgery

  • Transsphenoidal Surgery (Endoscopic): Minimally invasive removal through the nasal passage; standard for most tumors.

  • Craniotomy: For large or complex tumors not accessible by endoscopy.

2. Medications

  • Dopamine Agonists (Cabergoline, Bromocriptine): For prolactinomas.

  • Somatostatin Analogs (Octreotide, Lanreotide): For growth hormone-secreting tumors.

  • Adrenal enzyme inhibitors: To control cortisol in Cushing’s disease.

3. Radiation Therapy

  • Stereotactic Radiosurgery (Gamma Knife, CyberKnife): Precise, non-invasive radiation.

  • External Beam Radiation: For residual or recurrent tumors.

4. Hormone Replacement Therapy

  • For patients with reduced pituitary function post-surgery or radiation.


Cost of Pituitary Tumor Treatment in India

Table 1: Average Pituitary Tumor Treatment Cost in India

Type of TreatmentMinimum Cost (INR)Maximum Cost (INR)Approx. USD Range
Diagnostic Workup (MRI + Hormone tests)₹40,000₹80,000$480 – $960
Endoscopic Transsphenoidal Surgery₹2,50,000₹5,00,000$3,010 – $6,020
Craniotomy (Complex cases)₹3,50,000₹6,00,000$4,220 – $7,230
Medication (per month)₹5,000₹50,000$60 – $600
Radiation Therapy (Gamma Knife/CyberKnife)₹2,00,000₹4,50,000$2,410 – $5,420
Hormone Replacement (per year)₹30,000₹1,00,000$360 – $1,200

Factors Affecting Pituitary Tumor Treatment Cost

  1. Tumor size and type – Functioning tumors may need lifelong medication in addition to surgery.

  2. Type of surgery – Endoscopic transsphenoidal is less invasive but requires high expertise.

  3. Need for radiation – Advanced stereotactic radiosurgery increases overall cost.

  4. Hormone therapy – Lifelong replacement therapy adds to long-term expenses.

  5. Hospital location – Metro cities with specialized neurosurgical centers may charge more.

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