Gallbladder Cancer Treatment in India

Gallbladder cancer is a relatively rare but aggressive cancer that begins in the gallbladder, a small organ beneath the liver that stores bile. Because symptoms are often vague and appear late, gallbladder cancer is usually diagnosed in advanced stages.

In India, gallbladder cancer is more common in the northern and eastern regions, and treatment options include surgery, chemotherapy, radiation therapy, and targeted therapy, depending on the stage.

Symptoms of Gallbladder Cancer

  • Persistent abdominal pain (upper right side)

  • Unexplained weight loss

  • Loss of appetite

  • Nausea and vomiting

  • Jaundice (yellowing of skin and eyes)

  • Bloating or abdominal lump

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Risk Factors

  • Gallstones (most common risk factor)

  • Chronic gallbladder inflammation (cholecystitis)

  • Female gender (slightly higher risk)

  • Family history of gallbladder or biliary cancers

  • Obesity and poor diet

  • Exposure to certain industrial chemicals


Diagnosis of Gallbladder Cancer

  • Ultrasound & CT Scan: First-line imaging.

  • MRI / MRCP: To assess bile ducts and liver involvement.

  • Biopsy: Confirms diagnosis.

  • Endoscopic procedures (ERCP): To evaluate bile duct obstruction.

  • Blood tests: Liver function and tumor markers (CEA, CA 19-9).


Treatment Options for Gallbladder Cancer

1. Surgery

  • Cholecystectomy: Removal of gallbladder in early-stage cancer.

  • Extended Cholecystectomy: Removal of gallbladder, part of the liver, and nearby lymph nodes (standard for localized gallbladder cancer).

  • Palliative surgery: To relieve bile duct blockage in advanced stages.

2. Chemotherapy

  • Used in advanced or inoperable cancers.

  • Common regimens: Gemcitabine + Cisplatin.

  • May also be given after surgery (adjuvant) to reduce recurrence risk.

3. Radiation Therapy

  • External beam radiation to control local spread.

  • Sometimes combined with chemotherapy (chemoradiation).

4. Targeted Therapy & Immunotherapy

  • For advanced disease with genetic mutations or biomarkers.

  • Examples: FGFR inhibitors, PD-1 inhibitors (Nivolumab, Pembrolizumab).

5. Palliative & Supportive Care

  • Biliary stenting to relieve jaundice.

  • Pain management and nutritional support.


Cost of Gallbladder Cancer Treatment in India

The cost depends on stage, treatment type, and hospital infrastructure.

Table 1: Average Gallbladder Cancer Treatment Cost in India

Type of TreatmentMinimum Cost (INR)Maximum Cost (INR)Approx. USD Range
Surgery (Extended Cholecystectomy)₹2,50,000₹5,00,000$3,010 – $6,020
Chemotherapy (6 cycles)₹1,50,000₹5,00,000$1,810 – $6,020
Radiation Therapy₹1,50,000₹4,00,000$1,810 – $4,820
Targeted Therapy (per month)₹2,50,000₹5,00,000$3,010 – $6,020
Immunotherapy (per cycle)₹3,50,000₹6,00,000$4,220 – $7,230

Factors Affecting Gallbladder Cancer Treatment Cost

  1. Stage at diagnosis – early cases may only need surgery; advanced cases require multimodal therapy.

  2. Hospital infrastructure – specialized cancer centers may charge more.

  3. Choice of drugs – targeted and immunotherapy are costlier than standard chemotherapy.

  4. Post-surgery care – ICU, stenting, and management of complications affect costs.

  5. Frequency of imaging and follow-up – PET-CT and MRCP add to overall expense.

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